Amblyopia: A Multidisciplinary Approach, 1e by Merrick Moseley BSc PhD, Alistair Fielder MD

By Merrick Moseley BSc PhD, Alistair Fielder MD

This publication presents a precis and synthesis of present matters and study in the box of 1 of the main difficult paediatric eye stipulations - Amblyopia.

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Additional resources for Amblyopia: A Multidisciplinary Approach, 1e

Example text

The results divide along the lines of whether a strabismus is present or not; in the former case the deficit is mainly foveal, whereas in the latter case it is more evenly distributed across the visual field. With all these differences between strabismic and nonstrabismic amblyopia, it is hard to accept that amblyopia is a single entity; surely there must be at least two? A SNAKE: ANIMAL MODELS Animal models of human amblyopia have told us very little about the possible neural basis of the above deficits.

6 . - - - - - - , - - - - - - - - - - - - , AD CK -o~ Latency (ms) 512 0 Latency (ms) 512 Functional neuroimaging in amblyopia 55 2. The maximum power was always least with stimulation of the subject's amblyopic eye 3. The latency of this peak was always greatest with amblyopic-eye stimulation. The interocular differences in latency (mean: 14ms) and power (mean: 6 x 104 ff2) were significant (Wilcoxon T =0, two-tailed. 05). Global field power plots. 6. were calculated for a range of stimulus periodicities.

Thus, if the asymmetric dendritic fields of pyramidal cells were arranged in a spherically symmetric fashion, no external magnetic field would be generated because of mutual cancellation of the magnetic fields associated with individual cells. This is the arrangement encountered in many Functional neuroimaging in amblyopia 49 subcortical structures (Lewine and Orrison, 1995). However, the dendritic fields of pyramidal cells are oriented perpendicular to the surface of the cortex and over a given region are parallel to one another, allowing synchronous activity to be recorded.

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